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Anti-Junctional adhesion molecule C JAM3 Antibody

Boster Bio Anti-Junctional adhesion molecule C JAM3 Antibody catalog # A03436. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Junctional adhesion molecule C; JAM-C; JAM-2; Junctional adhesion molecule 3; JAM-3; Soluble form of JAM-C

Gene Name

JAM3

UniProt

Q9BX67

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 60-140

Clonality

Polyclonal

Tissue Specificity

Detected on round and elongated spermatids (at protein level) (PubMed:15372036) . Highest expression in placenta, brain and kidney. Significant expression is detected on platelets. Expressed in intestinal mucosa cells. Expressed in the vascular endothelium. Found in serum (at protein level) . Also detected in the synovial fluid of patients with rheumatoid arthritis, psoriatic arthritis or ostearthritis (at protein level) .

Applications

WB, ELISA

Purification

JAM3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Mediates cell-cell adhesion (PubMed:11590146, PubMed:12208882, PubMed:15194813) . Functions as counter-receptor for JAM2 (PubMed:11590146) . Functions as a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (PubMed:12208882, PubMed:15194813) . Plays a role in angiogenesis (PubMed:23255084) . May play a role in the regulation of cell migration (Probable) . Required for normal polarization and acrosome formation in developing spermatids, and for normal male fertility (By similarity) .

Molecular Weight

35020 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Junctional adhesion molecule C

Subcellular Location

Cell membrane

Protein Name

Junctional adhesion molecule C

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