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Anti-INSI2 INSIG2 Antibody

Boster Bio Anti-INSI2 INSIG2 Antibody catalog # A03906. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Insulin-induced gene 2 protein; INSIG-2; INSIG2;

Gene Name

INSIG2

UniProt

Q9Y5U4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 40-120

Clonality

Polyclonal

Applications

WB, ELISA

Purification

INSI2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs) . Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Molecular Weight

24778 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Insulin-induced gene 2 protein

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Insulin-induced gene 2 protein

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