Anti-I10R2 IL10RB Antibody

Boster Bio Anti-I10R2 IL10RB Antibody catalog # A03536. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Interleukin-10 receptor subunit beta; IL-10 receptor subunit beta; IL-10R subunit beta; IL-10RB; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; CRF2-4; Interleukin-10 receptor subunit 2; IL-10R subunit 2; IL-10R2; CDw210b; IL10RB; CRFB4, D21S58, D21S66;

Gene Name

IL10RB

UniProt

Q08334

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 240-320

Clonality

Polyclonal

Applications

WB, ELISA

Purification

I10R2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.