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Anti-CD320 antigen CD320 Antibody

Boster Bio Anti-CD320 antigen CD320 Antibody catalog # A06409. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CD320 antigen;8D6 antigen

Gene Name

CD320

UniProt

Q9NPF0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 100-180

Clonality

Polyclonal

Tissue Specificity

Detected in the germinal center (GC) of lymphoid follicles (at protein level) (PubMed:11418631) . Expressed abundantly on follicular dendritic cells (FDCs) (PubMed:10727470) .

Applications

WB, ELISA

Purification

CD320 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389) . Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213) . Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470) . Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631) . Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631) . CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed:11418631) .

Molecular Weight

28991 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06409

Product MSDS

https://www.bosterbio.com/msds?sku=A06409

Fragment

IgG

Other Gene Names

CD320 antigen

Subcellular Location

Cell membrane

Protein Name

CD320 antigen

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