Anti-RNF6 Antibody
Boster Bio Anti-RNF6 Antibody catalog # A09820. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
E3 ubiquitin-protein ligase RNF6;2.3.2.27; RING-type E3 ubiquitin transferase RNF6 ; RNF6; SPG2;
Gene Name
RNF6
UniProt
Q9Y252
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from human protein at AA range: 470-550
Clonality
Polyclonal
Tissue Specificity
Weakly expressed in peripheral blood, spleen, prostate, testis and ovary. According to PubMed:18368307, it is preferentially expressed in testis and ovary and hardly detected in other tissues.
Applications
WB, ELISA
Purification
RNF6 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Form
Liquid
Function
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Molecular Weight
78091 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
E3 ubiquitin-protein ligase RNF6
Subcellular Location
Nucleus
Protein Name
E3 ubiquitin-protein ligase RNF6
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