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Anti-RNF6 Antibody

Boster Bio Anti-RNF6 Antibody catalog # A09820. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase RNF6;2.3.2.27; RING-type E3 ubiquitin transferase RNF6 ; RNF6; SPG2;

Gene Name

RNF6

UniProt

Q9Y252

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from human protein at AA range: 470-550

Clonality

Polyclonal

Tissue Specificity

Weakly expressed in peripheral blood, spleen, prostate, testis and ovary. According to PubMed:18368307, it is preferentially expressed in testis and ovary and hardly detected in other tissues.

Applications

WB, ELISA

Purification

RNF6 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

Molecular Weight

78091 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A09820

Product MSDS

https://www.bosterbio.com/msds?sku=A09820

Fragment

IgG

Other Gene Names

E3 ubiquitin-protein ligase RNF6

Subcellular Location

Nucleus

Protein Name

E3 ubiquitin-protein ligase RNF6

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