What is the catalog number for Anti-MLL4 KMT2B Antibody?

The catalog number for Anti-MLL4 KMT2B Antibody is A05680-1.

What sizes are available for Anti-MLL4 KMT2B Antibody?

Anti-MLL4 KMT2B Antibody is available in the following size(s): 100 µL.

Is Anti-MLL4 KMT2B Antibody in stock?

Anti-MLL4 KMT2B Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MLL4 KMT2B Antibody?

The safety data sheet for Anti-MLL4 KMT2B Antibody is available here: https://www.bosterbio.com/msds?sku=A05680-1.

Anti-MLL4 KMT2B Antibody

Boster Bio Anti-MLL4 KMT2B Antibody catalog # A05680-1. Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Histone-lysine N-methyltransferase 2B; Lysine N-methyltransferase 2B;2.1.1.43; Myeloid/lymphoid or mixed-lineage leukemia protein 4; Trithorax homolog 2; WW domain-binding protein 7; WBP-7; KMT2B; HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7;

Gene Name

KMT2B

UniProt

Q9UMN6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 1060-1140

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Highest levels in testis. Also found in brain with higher expression in the cerebellum than in any other region, bone marrow, heart, muscle, kidney, placenta, spleen, thymus, prostate, ovary, intestine, colon, peripheral blood lymphocytes and pancreas. Often amplified in pancreatic carcinomas.

Applications

IHC

Purification

MLL4 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

IHC-p 1:50-300

Form

Liquid

Function

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.