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Anti-MK04 MAPK4 Antibody

Boster Bio Anti-MK04 MAPK4 Antibody catalog # A06298. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4;2.7.11.24; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK; MAPK4; ERK4, PRKM4;

Gene Name

MAPK4

UniProt

P31152

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 410-490

Clonality

Polyclonal

Tissue Specificity

High expression in heart and brain.

Applications

WB, ELISA

Purification

MK04 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity) . .

Molecular Weight

65922 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Mitogen-activated protein kinase 4

Subcellular Location

Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .

Protein Name

Mitogen-activated protein kinase 4

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