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Anti-NR2C1 Antibody

Boster Bio Anti-NR2C1 Antibody catalog # A06568-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nuclear receptor subfamily 2 group C member 1; Orphan nuclear receptor TR2; Testicular receptor 2; NR2C1; TR2;

Gene Name

NR2C1

UniProt

P13056

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human protein at AA range: 40-120

Clonality

Polyclonal

Applications

WB, ELISA

Purification

NR2C1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid- regulated preadipocyte proliferation.

Molecular Weight

67315 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Nuclear receptor subfamily 2 group C member 1

Subcellular Location

Nucleus

Protein Name

Nuclear receptor subfamily 2 group C member 1

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