What is the catalog number for Anti-LRP6 Antibody?

The catalog number for Anti-LRP6 Antibody is A00970.

What sizes are available for Anti-LRP6 Antibody?

Anti-LRP6 Antibody is available in the following size(s): 100 µL.

Is Anti-LRP6 Antibody in stock?

Anti-LRP6 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-LRP6 Antibody?

The safety data sheet for Anti-LRP6 Antibody is available here: https://www.bosterbio.com/msds?sku=A00970.

Anti-LRP6 Antibody

Boster Bio Anti-LRP6 Antibody catalog # A00970. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Low-density lipoprotein receptor-related protein 6; LRP-6; LRP6;

Gene Name

LRP6

UniProt

O75581

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 1420-1500

Clonality

Polyclonal

Tissue Specificity

Widely coexpressed with LRP5 during embryogenesis and in adult tissues.

Applications

WB, ELISA

Purification

LRP6 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Form

Liquid

Function

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor- ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3- mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity) .

Molecular Weight

180429 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Low-density lipoprotein receptor-related protein 6

Subcellular Location

Cell membrane

Protein Name

Low-density lipoprotein receptor-related protein 6

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