Anti-Hu CD200 Purified Monoclonal Antibody
Boster Bio Anti-Hu CD200 Purified Monoclonal Antibody (Catalog# M01512) . Tested in Flow Cytometry, IHC-P, IHC-F application (s) . This antibody reacts with Human.
Product Specifications
Background
CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.
Synonyms
MRC, MOX, OX-2
Gene Name
CD200
UniProt
P41217
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human CD200. The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.
Clonality
Monoclonal
Clone
Clone: OX-104
Applications
Flow Cytometry, IHC-P, IHC-F
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Dilution
Flow cytometry: 1-4 μg/ml.
Form
Liquid
Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Molecular Weight
31264 MW
Shipping Conditions
Available
Storage Conditions
Store at 2-8°C. Do not freeze.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=M01512
Product MSDS
https://www.bosterbio.com/msds?sku=M01512
Fragment
Mouse IgG1 kappa
Other Gene Names
CD200 molecule
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
OX-2 membrane glycoprotein
Curated Selection
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