Anti-Hu CD300e Purified Monoclonal Antibody
Boster Bio Anti-Hu CD300e Purified Monoclonal Antibody (Catalog# M11226) . Tested in Flow Cytometry, IP, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.
Synonyms
CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
Gene Name
CD300E
UniProt
Q496F6
Host
Mouse
Reactivity
Human
Immunogen
CD300e-HA-transfected cells. The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
Clonality
Monoclonal
Clone
Clone: UP-H2
Tissue Specificity
Present on the surface of mature hematopoietic cells of the monocyte and myeloid lineages (at protein level) .
Applications
Flow Cytometry, IP, WB
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Dilution
Flow cytometry: 1-4 μg/ml.
Form
Liquid
Function
Probably acts as an activating receptor.
Molecular Weight
22918 MW
Shipping Conditions
Available
Storage Conditions
Store at 2-8°C. Do not freeze.
Fragment
Mouse IgG1 kappa
Other Gene Names
CD300e molecule
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Name
CMRF35-like molecule 2
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