Anti-DDIT4L Purified Monoclonal Antibody
Boster Bio Anti-DDIT4L Purified Monoclonal Antibody (Catalog# M09701) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
Synonyms
DDIT4L, REDD2, Rtp801L
Gene Name
DDIT4L
UniProt
Q96D03
Host
Mouse
Reactivity
Human
Immunogen
N-terminal recombinant fragment of human DDIT4L (amino acids 2-98) . The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.
Clonality
Monoclonal
Clone
Clone: DDIT-03
Tissue Specificity
Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.
Applications
Flow Cytometry, WB
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Dilution
Flow cytometry: 1-4 μg/ml. Intracellular staining.
Form
Liquid
Function
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
Molecular Weight
21740 MW
Shipping Conditions
Available
Storage Conditions
Store at 2-8°C. Do not freeze.
Fragment
Mouse IgG1
Other Gene Names
DNA damage inducible transcript 4 like
Subcellular Location
Cytoplasm.
Protein Name
DNA damage-inducible transcript 4-like protein
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