Anti-DDIT4L Purified Monoclonal Antibody

Boster Bio Anti-DDIT4L Purified Monoclonal Antibody (Catalog# M09701) . Tested in Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.

Synonyms

DDIT4L, REDD2, Rtp801L

Gene Name

DDIT4L

UniProt

Q96D03

Host

Mouse

Reactivity

Human

Immunogen

N-terminal recombinant fragment of human DDIT4L (amino acids 2-98) . The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.

Clonality

Monoclonal

Clone

Clone: DDIT-03

Tissue Specificity

Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery.

Applications

Flow Cytometry, WB

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Dilution

Flow cytometry: 1-4 μg/ml. Intracellular staining.

Form

Liquid

Function

Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.

Molecular Weight

21740 MW

Shipping Conditions

Available

Storage Conditions

Store at 2-8°C. Do not freeze.

Fragment

Mouse IgG1

Other Gene Names

DNA damage inducible transcript 4 like

Subcellular Location

Cytoplasm.

Protein Name

DNA damage-inducible transcript 4-like protein

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