Anti-Hu CD82 Purified Monoclonal Antibody
Boster Bio Anti-Hu CD82 Purified Monoclonal Antibody (Catalog# M02300-1) . Tested in Flow Cytometry, IP, WB, IHC-P, ICC application (s) . This antibody reacts with Human.
Product Specifications
Background
CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.
Synonyms
R2, 4F9, C33, IA4, ST6, GR15, KAI1, SAR2, TSPAN27
Gene Name
CD82
UniProt
P27701
Host
Mouse
Reactivity
Human
Immunogen
C91/PL (human HTLV-1+ T cell line) . The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.
Clonality
Monoclonal
Clone
Clone: C33
Tissue Specificity
Lymphoid specific.
Applications
Flow Cytometry, IP, WB, IHC-P, ICC
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Dilution
Flow cytometry: 1-4 µg/ml
Form
Liquid
Function
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Molecular Weight
29626 MW
Shipping Conditions
Available
Storage Conditions
Store at 2-8°C. Do not freeze.
Fragment
Mouse IgG2a
Other Gene Names
CD82 molecule
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Name
CD82 antigen
Curated Selection
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