Anti-TRIM Purified TRAT1 Monoclonal Antibody
Boster Bio Anti-TRIM Purified TRAT1 Monoclonal Antibody (Catalog# M11223) . Tested in Flow Cytometry, IP, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
Synonyms
TRAT, TCRIM
Gene Name
TRAT1
UniProt
Q6PIZ9
Host
Mouse
Reactivity
Human
Immunogen
Recombinant intracellular domain (aa 29-186) of human TRIM. The antibody TRIM-04 recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
Clonality
Monoclonal
Clone
Clone: TRIM-04
Tissue Specificity
Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level) .
Applications
Flow Cytometry, IP, WB
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Form
Liquid
Function
Stabilizes the TCR (T-cell antigen receptor) /CD3 complex at the surface of T-cells.
Molecular Weight
21211 MW
Shipping Conditions
Available
Storage Conditions
Store at 2-8°C. Do not freeze.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=M11223
Product MSDS
https://www.bosterbio.com/msds?sku=M11223
Fragment
Mouse IgG2a
Other Gene Names
T cell receptor associated transmembrane adaptor 1
Subcellular Location
Cell membrane
Protein Name
T-cell receptor-associated transmembrane adapter 1
Curated Selection
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