Anti-Chondroadherin CHAD Antibody

Boster Bio Anti-Chondroadherin CHAD Antibody (Catalog # A03177) . Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2) . It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4) . Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5) .

Synonyms

Cartilage leucine-rich protein, CHAD, SLRR4A

Gene Name

CHAD

UniProt

O15335

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

Chondroadherin antibody is human and mouse reactive. Chondroadherin antibody is predicted to not cross-react with CHADL protein.

Immunogen

Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin.

Clonality

Polyclonal

Tissue Specificity

Present in chondrocytes at all ages.

Applications

ELISA, WB, ICC

Field of Research

Stem Cells, Homeostasis

Purification

Chondroadherin antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha (2) beta (1) . May play an important role in the regulation of chondrocyte growth and proliferation (By similarity) . .

Molecular Weight

40476 MW

Shipping Conditions

Available

Storage Conditions

Chondroadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Chondroadherin

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Prediction Reactivity

Bovine

Protein Name

Chondroadherin

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS8318757-01 10 nmol

mmu-miR-467a-3p miRNA Antagomir

Ask

View Details

MBS8318757-02 20 nmol

mmu-miR-467a-3p miRNA Antagomir

Ask

View Details

MBS8318757-03 5x 20 nmol

mmu-miR-467a-3p miRNA Antagomir

Ask

View Details

MBS3244782-01 0.1 mg

SNRPD3 Peptide - middle region

Ask

View Details

MBS3244782-02 5x 0.1 mg

SNRPD3 Peptide - middle region

Ask

View Details

GWB-MN157D 50 µg

GRHL2 Antibody

Ask

View Details