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Anti-VTI1a Antibody

Boster Bio Anti-VTI1a Antibody (Catalog # A06649-1) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1) . They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3) . VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4) . VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5) .

Synonyms

Vesicle transport through interaction with t-SNAREs 1A, MMDS3, MVti1, VTI1RP2, Vti1-rp2

Gene Name

VTI1A

UniProt

Q96AJ9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

VTI1a antibody is human, mouse and rat reactive. At least two isoforms of VTI1a are known to exist; this antibody will detect both isoforms. VTI1a antibody is predicted to not cross-react with VTI1b.

Immunogen

VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a. The immunogen is located within amino acids 50 - 100 of VTI1a.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P

Field of Research

Homeostasis

Purification

VTI1a antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.

Molecular Weight

25218 MW

Shipping Conditions

Available

Storage Conditions

VTI1a antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06649-1

Product MSDS

https://www.bosterbio.com/msds?sku=A06649-1

Fragment

IgG

Other Gene Names

Vesicle transport through interaction with t-SNAREs 1A

Subcellular Location

Cytoplasmic vesicle

Protein Name

Vesicle transport through interaction with t-SNAREs 1A

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