Anti-DEPDC1B Antibody
Boster Bio Anti-DEPDC1B Antibody (Catalog # A11735) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.
Product Specifications
Background
The DEP domain-containing 1B (DEPDC1B) protein was initially identified as a radiation response biomarker in human lymphoblastoid cell lines (1) . Like the related protein DEPDC1A, expression of DEPDC1B correlates with a poor prognosis in cancer patients (2,3) . Studies have shown that DEPDC1B levels are upregulated in non-small cell lung cancer (NSCLC) and have an inverse correlation with patient survival. Ectopic expression of DEPDC1B in NSCLC activated Wnt/B-catenin signaling and enhanced cell migration and invasion while silencing DEPDC1B expression suppressed these traits (2) .
Synonyms
DEP domain-containing 1B, DEP1B, BRCC3, Breast cancer cell 3, XTP1
Gene Name
DEPDC1B
UniProt
Q8WUY9
Host
Rabbit
Reactivity
Human
Cross Reactivity
DEPDC1B antibody is human specific. At least two isoforms are known to exist; this antibody will only detect the largest isoform. DEPDC1B antibody is predicted to not cross-react with DEPDC1A.
Immunogen
DEPDC1B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DEPDC1B. The immunogen is located within the last 50 amino acids of DEPDC1B.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P
Field of Research
Cancer, Cell Cycle
Purification
DEPDC1B antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Molecular Weight
61771 MW
Shipping Conditions
Available
Storage Conditions
DEPDC1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Fragment
IgG
Other Gene Names
DEP domain containing 1B
Prediction Reactivity
Mouse, Chicken
Protein Name
DEP domain containing 1B
Frequently Asked Questions
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