Anti-Hexokinase 1 HK1 Antibody

Boster Bio Anti-Hexokinase 1 HK1 Antibody (Catalog # A01504-2) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1) . Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2) . Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3) . It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4) .

Synonyms

HK, HXK

Gene Name

HK1

UniProt

P19367

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

Hexokinase 1 antibody is human, mouse and rat reactive. Multiple isoforms of Hexokinase 1 are known to exist.

Immunogen

Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1. The immunogen is located within amino acids 830 - 880 of Hexokinase 1.

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

Hexokinase 1 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Molecular Weight

102486 MW

Shipping Conditions

Available

Storage Conditions

Hexokinase 1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Hexokinase 1

Subcellular Location

Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.

Prediction Reactivity

Bovine

Protein Name

Hexokinase 1

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