Anti-AJAP1 Antibody

Boster Bio Anti-AJAP1 Antibody (Catalog # A07801) . Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1) . It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2) . AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3) . This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4) .

Synonyms

Adherens junctions associated protein 1, Membrane protein shrew-1, MOT8, SHREW1

Gene Name

AJAP1

UniProt

Q9UKB5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

AJAP1 antibody is human, mouse and rat reactive.

Immunogen

AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1. The immunogen is located within amino acids 290 - 340 of AJAP1.

Clonality

Polyclonal

Tissue Specificity

Expressed in uterus and pancreas (at protein level) .

Applications

ELISA, WB, ICC

Field of Research

Homeostasis, Cancer

Purification

AJAP1 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in cell adhesion and cell migration.

Molecular Weight

44536 MW

Shipping Conditions

Available

Storage Conditions

AJAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Adherens junctions associated protein 1

Subcellular Location

Basolateral cell membrane; Single-pass type III membrane protein. Apical cell membrane; Single-pass type III membrane protein. Cell junction, adherens junction. Mainly basolateral. Localization is mediated by AP1M2.