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Anti-Myosin-8 MYH8 Antibody

Boster Bio Anti-Myosin-8 MYH8 Antibody (Catalog # A08502) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1) . MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal) is a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction (2,3) . This gene is predominantly expressed in fetal skeletal muscle. MYH8 is regulated by phosphorylation via myosin light chain kinase (MLCK) and by intracellular Ca2+ concentrations (3) . A mutation in this gene results in trismus-pseudocamptodactyly syndrome (4) .

Synonyms

Myosin heavy chain 8, Myosin-8, Myosin heavy chain skeletal muscle perinatal, MyHC-perinatal, MyHC-peri, MyHC-pn, gtMHC-F

Gene Name

MYH8

UniProt

P13535

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

MYH8 antibody is human, mouse and rat reactive. MYH8 antibody is predicted to not cross-react with other members of the myosin heavy chain family.

Immunogen

MYH8 antibody was raised against a 19 amino acid peptide near the amino terminus of human MYH8. The immunogen is located within amino acids 60 - 110 of MYH8.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

MYH8 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Muscle contraction.

Molecular Weight

222763 MW

Shipping Conditions

Available

Storage Conditions

MYH8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Myosin, heavy chain 8, skeletal muscle, perinatal

Subcellular Location

Cytoplasm, myofibril. Thick filaments of the myofibrils.

Prediction Reactivity

Horse, Rabbit, Pig, Bovine, Chicken

Protein Name

Myosin, heavy chain 8, skeletal muscle, perinatal

Curated Selection

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