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Anti-SKI2W SKIV2L Antibody

Boster Bio Anti-SKI2W SKIV2L Antibody (Catalog # A04982) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2) . SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2) . The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4) .

Synonyms

Superkiller viralicidic activity 2-like, DDX13, Helicase-like protein, Helicase SKI2W, HLP, SKI2, SKIV2, SKIV2L

Gene Name

SKIV2L

UniProt

Q15477

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist; this antibody will detect both isoforms.

Immunogen

SKI2W antibody was raised against a 16 amino acid peptide near the amino terminus of human SKI2W. The immunogen is located within amino acids 60 - 110 of SKI2W.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

SKI2W antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Helicase; has ATPase activity. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) .

Molecular Weight

137755 MW

Shipping Conditions

Available

Storage Conditions

SKI2W antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)

Subcellular Location

Nucleus . Cytoplasm .

Protein Name

SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)

Frequently Asked Questions

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