Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody

Boster Bio Anti-Kin of IRRE-like protein 2 KIRREL2 Antibody (Catalog # A07812) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

KIRREL2, also known as nephrin-like 3, is a type I transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules (1) . KIRREL2 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues (1,2) . KIRREL2 has been found to be expressed in beta cells of pancreatic islets and is involved in the regulation of both glomerular and neural development (3,4) . Downregulation of KIRREL2 is implicated in several proteinuric diseases (4,5) .

Synonyms

Kin of irregular chiasm-like protein 2, Kin of IRRE-like protein 2, NEPH3, Nephrin-like protein 3, NLG1, FILTRIN

Gene Name

KIRREL2

UniProt

Q6UWL6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

KIRREL2 antibody is human, mouse and rat reactive. At least five isoforms are are known to exist. This antibody is predicted to not cross-react with other members of the KIRREL protein family.

Immunogen

KIRREL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KIRREL2. The immunogen is located within amino acids 550 - 600 of KIRREL2.