What is the catalog number for Anti-NDST2 Antibody?

The catalog number for Anti-NDST2 Antibody is A08570.

Is Anti-NDST2 Antibody in stock?

Anti-NDST2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-NDST2 Antibody?

The safety data sheet for Anti-NDST2 Antibody is available here: https://www.bosterbio.com/msds?sku=A08570.

Anti-NDST2 Antibody

Boster Bio Anti-NDST2 Antibody (Catalog # A08570) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2) protein, also known as N-heparan sulfate sulfotransferase 2, and the highly related protein NDST1 have key roles in the sulfation of heparan sulfate proteoglycans, molecules that are present of cell surfaces and the extracellular matrix (1,2) . NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessary for induction of adipocytes and neural cells (3) .

Synonyms

NST2, HSST2, N-heparan sulfate sulfotransferase 2, NDST-2

Gene Name

NDST2

UniProt

P52849

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

NDST2 antibody is human, mouse and rat reactive. At least two isoforms of NDST2 are known to exist; this antibody will only detect the larger isoform. NDST2 antibody is predicted not to cross-react with other members of the NDST protein family.

Immunogen

NDST2 antibody was raised against a 16 amino acid peptide near the amino terminus of human NDST2. The immunogen is located within amino acids 20 - 70 of NDST2.

Clonality

Polyclonal

Applications

ELISA, WB, IF

Field of Research

Stem Cells

Purification

NDST2 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413) .