Anti-Treslin TICRR Antibody

Boster Bio Anti-Treslin TICRR Antibody (Catalog # A08002) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Product Specifications

Background

TopBP1-interacting checkpoint and replication regulator, Treslin, chromosome 15 open reading frame 42, C15ORF42

Synonyms

SLD3, Treslin, C15orf42, TopBP1-interacting checkpoint and replication regulator

Gene Name

TICRR

UniProt

Q7Z2Z1

Host

Rabbit

Reactivity

Human

Cross Reactivity

TICRR antibody is human specific. At least two isoforms of TICRR are known to exist.

Immunogen

TICRR antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TICRR. The immunogen is located within amino acids 1840 - 1890 of TICRR.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Cell Cycle

Purification

TICRR antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre- initiation complex (pre-IC) . Required to prevent mitotic entry after treatment with ionizing radiation.