Anti-POU2F3 Antibody

Boster Bio Anti-POU2F3 Antibody (Catalog # A09040) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1) . POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2) . It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3) . POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4) .

Synonyms

PLA1, OCT11, PLA-1, Epoc-1, OCT-11, OTF-11, Skn-1a, OTF11, PLA1, POU domain, class 2, transcription factor 3, Octamer-binding protein 11, 41923

Gene Name

POU2F3

UniProt

Q9UKI9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Immunogen

POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3. The immunogen is located within amino acids 370 - 420 of POU2F3.

Clonality

Polyclonal

Tissue Specificity

Specifically expressed in epidermis and cultured keratinocytes.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Stem Cells

Purification

POU2F3 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') . Regulated the expression of a number of genes such as SPRR2A or placental lactogen.