Anti-GDPD5 Antibody

Boster Bio Anti-GDPD5 Antibody (Catalog # A10116) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2,3) . Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4) .

Synonyms

GDE2, PP1665, GDE2, PP6037, PP9363, UNQ1850/PRO3580, Glycerophosphodiester phosphodiesterase domain-containing protein 5, Glycerophosphodiester phosphodiesterase 2

Gene Name

GDPD5

UniProt

Q8WTR4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.

Immunogen

GDPD5 antibody was raised against an 18 amino acid peptide near the amino terminus of human GDPD5. The immunogen is located within the first 50 amino acids of GDPD5.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Stem Cells

Purification

GDPD5 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.