Anti-SPINSTER SPNS1 Antibody

Boster Bio Anti-SPINSTER SPNS1 Antibody (Catalog # A09902) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Product Specifications

Background

SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1) . SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2) . The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3) .

Synonyms

LAT, nrs, SPIN1, SPINL, HSpin1, PP2030, PP20300, Protein spinster homolog 1

Gene Name

SPNS1

UniProt

Q9H2V7

Host

Rabbit

Reactivity

Human

Cross Reactivity

SPINSTER antibody is human specific. At least four isoforms of SPINSTER are known to exist. This antibody is predicted to not cross-react with other members of the spinster family of proteins.

Immunogen

SPINSTER antibody was raised against an 18 amino acid peptide near the amino terminus of human SPINSTER. The immunogen is located within the first 50 amino acids of SPINSTER.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Autophagy

Purification

SPINSTER antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Sphingolipid transporter (By similarity) . May be involved in necrotic or autophagic cell death.

Molecular Weight

56630 MW

Shipping Conditions

Available

Storage Conditions

SPINSTER antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Spinster homolog 1 (Drosophila)

Subcellular Location

Mitochondrion inner membrane

Prediction Reactivity

Bovine, Rat, Mouse

Protein Name

Spinster homolog 1 (Drosophila)

Curated Selection

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