Anti-TMIGD1 Antibody

Boster Bio Anti-TMIGD1 Antibody (Catalog # A16616) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2) . It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1) . TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4) . TMIGD1 has also been postulated to play a role in cell adhesion (2) .

Synonyms

TMIGD, UNQ9372, TMIGD, UNQ9372/PRO34164, Transmembrane and immunoglobulin domain-containing protein 1

Gene Name

TMIGD1

UniProt

Q6UXZ0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist; this antibody will detect both isoforms.

Immunogen

TMIGD1 antibody was raised against an 18 amino acid peptide near the center of human TMIGD1. The immunogen is located within amino acids 150 - 200 of TMIGD1.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Stem Cells

Purification

TMIGD1 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.