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Anti-APPBP2 Antibody

Boster Bio Anti-APPBP2 Antibody (Catalog # A11671-1) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1) . The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2) . APPBP2 has been found to be highly expressed in breast cancer (3) .

Synonyms

PAT1, APP-BP2, HS.84084, KIAA0228, PAT1, Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2

Gene Name

APPBP2

UniProt

Q92624

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist; this antibody will detect both isoforms.

Immunogen

APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Neuroscience

Purification

APPBP2 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Molecular Weight

66853 MW

Shipping Conditions

Available

Storage Conditions

APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Amyloid beta precursor protein (cytoplasmic tail) binding protein 2

Subcellular Location

Nucleus. Cytoplasm, cytoskeleton. Membrane ; Peripheral membrane protein . Associated with membranes and microtubules.

Protein Name

Amyloid beta precursor protein (cytoplasmic tail) binding protein 2

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