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Anti-Liprin-alpha-3 PPFIA3 Antibody

Boster Bio Anti-Liprin-alpha-3 PPFIA3 Antibody (Catalog # A11239) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1) . Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2) .

Synonyms

LPNA3, KIAA0654, Liprin-alpha-3, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3, PTPRF-interacting protein alpha-3

Gene Name

PPFIA3

UniProt

O75145

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

PPFIA3 antibody is human, mouse, and rat reactive.

Immunogen

PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3. The immunogen is located within amino acids 1100 - 1150 of PPFIA3.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in brain (PubMed:9624153) . Also detected in sperm (at protein level) (PubMed:23124857) .

Applications

ELISA, WB

Field of Research

Neuroscience

Purification

PPFIA3 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.

Molecular Weight

133496 MW

Shipping Conditions

Available

Storage Conditions

PPFIA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A11239

Product MSDS

https://www.bosterbio.com/msds?sku=A11239

Fragment

IgG

Other Gene Names

Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

Subcellular Location

Cytoplasm

Protein Name

Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

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