Anti-COMMD7 Antibody
Boster Bio Anti-COMMD7 Antibody (Catalog # A09709) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1) . It associates with the NF-kB complex and suppresses its transcriptional activity (2) . COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3) . COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4) . COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4) .
Synonyms
C20orf92, dJ1085F17.3, C20orf92, COMM domain-containing protein 7
Gene Name
COMMD7
UniProt
Q86VX2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
COMMD7 antibody is human, mouse and rat reactive. Multiple transcript variants encoding different isoforms have been found for COMMD7.
Immunogen
COMMD7 antibody was raised against a 19 amino acid peptide near the center of human COMMD7. The immunogen is located within amino acids 90 - 140 of COMMD7.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P, IF
Field of Research
Cancer, Cell Cycle
Purification
COMMD7 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237) . Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966) .
Molecular Weight
22540 MW
Shipping Conditions
Available
Storage Conditions
COMMD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Fragment
IgG
Other Gene Names
COMM domain containing 7
Subcellular Location
Cytoplasmic vesicle
Prediction Reactivity
Bovine
Protein Name
COMM domain containing 7
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