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Anti-B- and T-lymphocyte attenuator BTLA Antibody

Boster Bio Anti-B- and T-lymphocyte attenuator BTLA Antibody (Catalog # A03149-1) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Product Specifications

Background

The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1) . Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2) . Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3) .

Synonyms

BTLA1, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein

Gene Name

BTLA

UniProt

Q7Z6A9

Host

Rabbit

Reactivity

Human

Cross Reactivity

BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.

Immunogen

BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA. The immunogen is located within amino acids 170 - 220 of BTLA .

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Innate Immunity

Purification

BTLA Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.

Molecular Weight

32834 MW

Shipping Conditions

Available

Storage Conditions

BTLA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

B and T lymphocyte associated

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

B and T lymphocyte associated

Frequently Asked Questions

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