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Anti-DDC Antibody

Boster Bio Anti-DDC Antibody (Catalog # A01374) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1) . It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2) . It can form a homodimer and is expressed in the central nervous system (2) . DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4) . Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4) .

Synonyms

AADC, AADC, Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase

Gene Name

DDC

UniProt

P20711

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

DDC antibody is human, mouse and rat reactive.

Immunogen

DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Neuroscience

Purification

DDC Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.

Molecular Weight

53926 MW

Shipping Conditions

Available

Storage Conditions

DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Dopa decarboxylase (aromatic L-amino acid decarboxylase)

Prediction Reactivity

Bovine, Guinea Pig, Pig

Protein Name

Dopa decarboxylase (aromatic L-amino acid decarboxylase)

Frequently Asked Questions

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