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Anti-Golgin subfamily A member 5 GOLGA5 Antibody

Boster Bio Anti-Golgin subfamily A member 5 GOLGA5 Antibody (Catalog # A02176) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1) . It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2) . As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4) . Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5) .

Synonyms

RFG5, GOLIM5, ret-II, RETII, RFG5, PIG31, Golgin subfamily A member 5, Cell proliferation-inducing gene 31 protein

Gene Name

GOLGA5

UniProt

Q8TBA6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.

Immunogen

GOLGA5 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GOLGA5. The immunogen is located within amino acids 540 - 590 of GOLGA5.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in seminiferous tubules and Leydig cells in testis, and detected at much lower levels in the other tissues tested. Expression is very low or not detectable in spermatozoa.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

GOLGA5 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

Molecular Weight

83024 MW

Shipping Conditions

Available

Storage Conditions

GOLGA5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Golgin A5

Subcellular Location

Golgi apparatus membrane

Protein Name

Golgin A5

Frequently Asked Questions

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