Anti-TLX3 Antibody
Boster Bio Anti-TLX3 Antibody (Catalog # A14535) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL) .
Synonyms
RNX, HOX11L2, T-cell leukemia homeobox protein 3, Homeobox protein Hox-11L2
Gene Name
TLX3
UniProt
O43711
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
TLX3 antibody is predicted to not cross-react with other TLX proteins.
Immunogen
TLX3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX3. The immunogen is located within the first 50 amino acids of TLX3.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P, IF
Field of Research
Stem Cells
Purification
TLX3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Molecular Weight
31867 MW
Shipping Conditions
Available
Storage Conditions
TLX3 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
T-cell leukemia homeobox 3
Subcellular Location
Nucleus .
Protein Name
T-cell leukemia homeobox 3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
