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Anti-CNRIP1 Antibody

Boster Bio Anti-CNRIP1 Antibody (Catalog # A11640) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The CNRIP1 (cannabinoid receptor interacting protein 1) protein is a G-protein coupled receptor which interacts with the C-terminal tail of cannabinoid receptor 1 (CB1) and is thought to play a role in synaptic plasticity, analgesia, appetite, and neuroprotection. One isoform of CNRIP1, CNRIP1a, modulates the constitutive CB1 receptor activity in the central nervous system (CNS), while the role of the shorter isoform CNRIP1b is yet unknown. CNRIP1 has been suggested as a potential target for CNS drug discovery.

Synonyms

CRIP1, C2orf32, CB1 cannabinoid receptor-interacting protein 1, CRIP-1

Gene Name

CNRIP1

UniProt

Q96F85

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least two isoforms of CNRIP1 are known to exist; this antibody will detect both isoforms.

Immunogen

CNRIP1 antibody was raised against a 15 amino acid peptide near the center of human CNRIP1. The immunogen is located within amino acids 50 - 100 of CNRIP1.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Neuroscience

Purification

CNRIP1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect.

Molecular Weight

18648 MW

Shipping Conditions

Available

Storage Conditions

CNRIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Cannabinoid receptor interacting protein 1

Prediction Reactivity

Bovine

Protein Name

Cannabinoid receptor interacting protein 1

Frequently Asked Questions

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