Anti-Transmembrane protein 135 TMEM135 Antibody

Boster Bio Anti-Transmembrane protein 135 TMEM135 Antibody (Catalog # A14036) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The transmembrane protein 135 (TMEM135), also known as peroxisomal membrane protein 52 (PMP52), was initially identified as a protein that might be critical for adipogenesis and osteoblastogenesis. Further studies have indicated that TMEM135 may be part of a regulatory circuit that plays an important role in fat metabolism and energy expenditure in both C. elegans as well as mammalian organisms. Finally, recent experiments has suggested that TMEM135 may be an additional driver of breast cancer.

Synonyms

PMP52, Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52

Gene Name

TMEM135

UniProt

Q86UB9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least two isoforms of TMEM135 are known to exist; this antibody will detect both isoforms.

Immunogen

TMEM135 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TMEM135 . The immunogen is located within the last 50 amino acids of TMEM135.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Obesity

Purification

TMEM135 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in mitochondrial metabolism by regulating the balance between mitochondrial fusion and fission. May act as a regulator of mitochondrial fission that promotes DNM1L-dependent fission through activation of DNM1L. May be involved in peroxisome organization.