What is the catalog number for Anti-MTERFD1 MTERF3 Antibody?

The catalog number for Anti-MTERFD1 MTERF3 Antibody is A10983.

What sizes are available for Anti-MTERFD1 MTERF3 Antibody?

Anti-MTERFD1 MTERF3 Antibody is available in the following size(s): 0.1 mg.

Is Anti-MTERFD1 MTERF3 Antibody in stock?

Anti-MTERFD1 MTERF3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MTERFD1 MTERF3 Antibody?

The safety data sheet for Anti-MTERFD1 MTERF3 Antibody is available here: https://www.bosterbio.com/msds?sku=A10983.

Anti-MTERFD1 MTERF3 Antibody

Boster Bio Anti-MTERFD1 MTERF3 Antibody (Catalog # A10983) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD1 is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It binds promoter DNA and acts as a mitochondrial transcription regulator. It has been suggested that only the phosphorylated form of MTERFD1 has transcription termination activity. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.

Synonyms

CGI-12, mTERF3, mTERF domain-containing protein 1, mitochondrial, Mitochondrial transcription termination factor 3

Gene Name

MTERFD1

UniProt

Q96E29

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.

Immunogen

MTERFD1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MTERFD1 . The immunogen is located within the last 50 amino acids of MTERFD1.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung.

Applications

ELISA, WB, ICC, IF

Field of Research

Cancer, Cell Cycle

Purification

MTERFD1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Binds promoter DNA and regulates initiation of transcription (PubMed:17662942) . Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity) . Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity) .