Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PRKCDBP CAVIN3 Antibody

Boster Bio Anti-PRKCDBP CAVIN3 Antibody (Catalog # A32244) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

The protein kinase C delta (PKC-δ ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.

Synonyms

SRBC, HSRBC, CAVIN3, cavin-3, SRBC, Protein kinase C delta-binding protein, Cavin-3, hSRBC

Gene Name

PRKCDBP

UniProt

Q969G5

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

It is predicted to not cross-react with other members of the cavin family.

Immunogen

Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP. The immunogen is located within amino acids 150 - 200 of PRKCDBP.

Clonality

Polyclonal

Tissue Specificity

Skeletal muscle, liver, stomach, lung, kidney and heart (at protein level) . Strongly expressed in mammary and epithelial cells.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Cancer, Cell Cycle

Purification

PRKCDBP Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Regulates the traffic and/or budding of caveolae (PubMed:19262564) . Plays a role in caveola formation in a tissue- specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface- dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity) .

Molecular Weight

27701 MW

Shipping Conditions

Available

Storage Conditions

PRKCDBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A32244

Product MSDS

https://www.bosterbio.com/msds?sku=A32244

Fragment

IgG

Other Gene Names

Protein kinase C, delta binding protei

Subcellular Location

Cytoplasm

Prediction Reactivity

Rat

Protein Name

Protein kinase C, delta binding protei

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human Galectin-3 Binding Protein ELISA Kit
IHULGALS3BPKT 1 Each

Human Galectin-3 Binding Protein ELISA Kit

Ask
View Details
CSDE1 Antibody
A18257-100UG 100 µg

CSDE1 Antibody

Ask
View Details
Prkca 3'UTR Lenti-reporter-Luc Vector
37636084 1.0 μg

Prkca 3'UTR Lenti-reporter-Luc Vector

Ask
View Details
LGALS1 Polyclonal Antibody, HRP Conjugated
A57098-100 100 µL

LGALS1 Polyclonal Antibody, HRP Conjugated

Ask
View Details