What is the catalog number for Anti-TYK2 Antibody?

The catalog number for Anti-TYK2 Antibody is A01642-1.

What sizes are available for Anti-TYK2 Antibody?

Anti-TYK2 Antibody is available in the following size(s): 0.1 mg.

Is Anti-TYK2 Antibody in stock?

Anti-TYK2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-TYK2 Antibody?

The safety data sheet for Anti-TYK2 Antibody is available here: https://www.bosterbio.com/msds?sku=A01642-1.

Anti-TYK2 Antibody

Boster Bio Anti-TYK2 Antibody (Catalog # A01642-1) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Synonyms

JTK1, Non-receptor tyrosine-protein kinase TYK2

Gene Name

TYK2

UniProt

P29597

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms.

Immunogen

Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2. The immunogen is located within amino acids 90 - 140 of TYK2.

Clonality

Polyclonal

Tissue Specificity

Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.

Applications

ELISA, WB, IF

Field of Research

Signal Transduction

Purification

TYK2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.