Anti-FRL1 FMNL1 Antibody

Boster Bio Anti-FRL1 FMNL1 Antibody (Catalog # A05377) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.

Synonyms

FMNL, FHOD4, KW-13, C17orf1, C17orf1B, FMNL, Formin-like protein 1, CLL-associated antigen KW-13

Gene Name

FMNL1

UniProt

O95466

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

FRL1 antibody is human, mouse and rat reactive. Three alternatively spliced transcript variants have been observed

Immunogen

Rabbit polyclonal FRL1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FRL1. The immunogen is located within the last 50 amino acids of FRL1.

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

ELISA, WB, IF

Field of Research

Homeostasis

Purification

FRL1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in the control of cell motility and survival of macrophages (By similarity) . Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.

Molecular Weight

121854 MW

Shipping Conditions

Available

Storage Conditions

FRL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.