Anti-TCTEX1D3 TCTE3 Antibody

Boster Bio Anti-TCTEX1D3 TCTE3 Antibody (Catalog # A13959) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A) . TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH) .

Synonyms

TCTEX1D3, TCTEX1D3, Tctex1 domain-containing protein 3, T-complex testis-specific protein 3, Tcte-3

Gene Name

TCTE3

UniProt

Q8IZS6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family

Immunogen

TCTEX1D3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCTEX1D3. The immunogen is located within the first 50 amino acids of TCTEX1D3.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in testis. Also expressed in brain, lung and trachea.

Applications

ELISA, WB, IF

Field of Research

Homeostasis

Purification

TCTEX1D3 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity) . .

Molecular Weight

23176 MW

Shipping Conditions

Available

Storage Conditions

TCTEX1D3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Other Gene Names

T-complex-associated-testis-expressed 3

Subcellular Location

Cytoplasm, cytoskeleton . Cytoplasmic granule . Membrane ; Peripheral membrane protein . Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis (By similarity) . .