Anti-Protein yippee-like 3 YPEL3 Antibody

Boster Bio Anti-Protein yippee-like 3 YPEL3 Antibody (Catalog # A14890) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Synonyms

Protein yippee-like 3

Gene Name

YPEL3

UniProt

P61236

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

YPEL3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human YPEL3. The immunogen is located within amino acids 20 - 70 of YPEL3.

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

ELISA, WB, ICC, IF

Field of Research

Cancer, Cell Cycle

Purification

YPEL3 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in proliferation and apoptosis in myeloid precursor cells. .

Molecular Weight

13608 MW

Shipping Conditions

Available

Storage Conditions

YPEL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.