Anti-Teashirt homolog 2 TSHZ2 Antibody

The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Recent experiments have shown that the expression of TSHZ2 is frequently downregulated in most breast and prostate cancers and its promoter was unmethylated in virtually all cases, suggesting this family of proteins may also be involved in carcinogenesis.

TSHZ2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TSHZ2. The immunogen is located within amino acids 30 - 80 of TSHZ2.

TSHZ2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.