Anti-Translocation protein SEC62 SEC62 Antibody

Boster Bio Anti-Translocation protein SEC62 SEC62 Antibody (Catalog # A05906) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.

Synonyms

HTP1, TP-1, Dtrp1, TLOC1, Translocation protein SEC62, Translocation protein 1

Gene Name

SEC62

UniProt

Q99442

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.

Immunogen

SEC62 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SEC62. The immunogen is located within amino acids 270 - 320 of SEC62.

Clonality

Polyclonal

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

SEC62 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Required for preprotein translocation. .

Molecular Weight

45862 MW

Shipping Conditions

Available

Storage Conditions

SEC62 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.