Anti-Paralemmin3 PALM3 Antibody
Boster Bio Anti-Paralemmin3 PALM3 Antibody (Catalog # A13680) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.
Product Specifications
Background
Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.
Synonyms
Paralemmin-3
Gene Name
PALM3
UniProt
A6NDB9
Host
Rabbit
Reactivity
Human
Cross Reactivity
At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform
Immunogen
Paralemmin3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Paralemmin3. The immunogen is located within amino acids 50 - 100 of Paralemmin3.
Clonality
Polyclonal
Applications
ELISA, WB, ICC, IF
Field of Research
Innate Immunity
Purification
Paralemmin3 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling.
Molecular Weight
71695 MW
Shipping Conditions
Available
Storage Conditions
Paralemmin3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
Paralemmin 3
Subcellular Location
Cytoplasm . Cell membrane ; Lipid-anchor .
Prediction Reactivity
Mouse
Protein Name
Paralemmin 3
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