Anti-Paralemmin3 PALM3 Antibody

Boster Bio Anti-Paralemmin3 PALM3 Antibody (Catalog # A13680) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Product Specifications

Background

Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.

Synonyms

Paralemmin-3

Gene Name

PALM3

UniProt

A6NDB9

Host

Rabbit

Reactivity

Human

Cross Reactivity

At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform

Immunogen

Paralemmin3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Paralemmin3. The immunogen is located within amino acids 50 - 100 of Paralemmin3.

Clonality

Polyclonal

Applications

ELISA, WB, ICC, IF

Field of Research

Innate Immunity

Purification

Paralemmin3 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling.

Molecular Weight

71695 MW

Shipping Conditions

Available

Storage Conditions

Paralemmin3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.