Anti-EIG121 KIAA1324 Antibody

Boster Bio Anti-EIG121 KIAA1324 Antibody (Catalog # A12119) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Product Specifications

Background

EIG121 (Estrogen-induced gene 121 protein) is thought to play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family. It is a 1013 amino acid single-pass transmembrane protein that, though expressed in normal endometrium, is overexpressed in endometriod tumors. As an evolutionarily conserved gene, EIG121 is also expressed during early xenopus development, showing maximum expression at the gastrula stage.

Synonyms

EIG, EIG1

Gene Name

KIAA1324

UniProt

Q6UXG2

Host

Rabbit

Reactivity

Human

Cross Reactivity

At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.

Immunogen

EIG121 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human EIG121. The immunogen is located within the last 50 amino acids of EIG121.

Clonality

Polyclonal

Tissue Specificity

Expressed in normal endometrium but overexpressed in endometroid tumors.

Applications

ELISA, WB, ICC, IF

Field of Research

Stem Cells

Purification

EIG121 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.

Molecular Weight

111382 MW

Shipping Conditions

Available

Storage Conditions

EIG121 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.