Anti-Transmembrane protein 204 TMEM204 Antibody

Boster Bio Anti-Transmembrane protein 204 TMEM204 Antibody (Catalog # A13438) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.

Synonyms

CLP24, C16orf30, CLP24, UNQ6509/PRO21434, Transmembrane protein 204, Claudin-like protein 24

Gene Name

TMEM204

UniProt

Q9BSN7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.

Immunogen

TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204. The immunogen is located within the last 50 amino acids of TMEM204.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in lung, heart, kidney and placenta. Lower expression in thymus, spleen, liver, testis and ovary. Expressed in endothelial and restricted epithelial cell populations.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

TMEM204 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.

Molecular Weight

24540 MW

Shipping Conditions

Available

Storage Conditions

TMEM204 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.