Anti-CCDC141 Antibody
Boster Bio Anti-CCDC141 Antibody (Catalog # A15486) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1) -binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
Synonyms
CAMDI, Coiled-coil domain-containing protein 141
Gene Name
CCDC141
UniProt
Q6ZP82
Host
Rabbit
Reactivity
Human, Mouse
Cross Reactivity
At least four isoforms of CCDC141 are known to exist.
Immunogen
CCDC141 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CCDC141. The immunogen is located within amino acids 40 - 90 of CCDC141.
Clonality
Polyclonal
Applications
ELISA, WB, IHC-P, IF
Field of Research
Homeostasis
Purification
CCDC141 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Plays a critical role in radial migration and centrosomal function.
Molecular Weight
166261 MW
Shipping Conditions
Available
Storage Conditions
CCDC141 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
Coiled-coil domain containing 141
Subcellular Location
Cytoplasm
Protein Name
Coiled-coil domain containing 141
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
